Freelite^®

Polyclonal Serum Freelite Chain Assay from "The Binding Site, UK" recommended by IMWG, The Binding Site Group Limited, United Kingdom.

The Freelite assay is composed of two sensitive and specific immunodiagnostic tests to measure kappa (κ) and lambda (λ) free light chains.

It is the only free light chain assay recommended by national and international guidelines.

What is Freelite

Freelite are sensitive and specific tests to measure kappa (κ) and lambda (λ) free light chains (FLCs). The assays are based on affinity purified polyclonal antibodies that are coated onto latex particles. These are used to produce nephelometric and turbidimetric kits; specific for κ FLCs and λ FLCs.

Antibody molecule showing the heavy and light chain structure, together with κ and λ FLCs.

Freelite reacts only with exposed free light chain epitopes which are hidden when the light chain is bound to the heavy chain.

Freelite is recommended for use in patients with monoclonal gammopathies including:

•  Light Chain Multiple Myeloma (LCMM)
•  Intact Immunoglobulin Multiple Myeloma (IIMM)
•  Smouldering Multiple Myeloma (SMM)
•  Non secretory Multiple Myeloma (NSMM)
• AL amyloidosis